I have Factor 5 Leiden - is it safe for me to have breast augmentation?


I want to get breast implants.  It was discovered while I was pregnant that I have Factor 5 Leiden disorder.  I was on Clexane whilst pregnant but was taken off of it at the end of my pregnancy.  My doctor said there was no need to take it at any other time except during pregnancy as it prevents miscarriage.  Is it OK for me now to safely have breast augmentation? 


The answer is yes providing your hematologist clears you for surgery and makes peri operative recommendations for your care around the time of surgery. Because anti-clotting drugs like Lovenox most likely will be required BEFORE the beginning of such surgery you will have an increased chance for peri operative complications such as bleeding, hematoma, Deep Venous Thrombosis, Pulmonary Embolus, etc.


Gary R Culbertson, MD, FACS


Breast augmentation is a relatively short procedure with minimal risks. However, one of those risks is deep vein thrombosis and pulmonary embolus, a problem that can be fatal. Up to 30% of people with this problem after surgery have Factor 5 Leiden disorder. Therefore, you will need perioperative anticoagulation to protect you from this problem. Have your plastic surgeon talk to your hematologist to decide how to accomplish this.

R.T. Buchanan, MD


It will be important for your plastic surgeon to work together with your hematologist to determine if and when you will need to be treated. In my practice I have used a course of Lovenox to try to protect my patients from developing a blood clot around the time of a surgery. The risk of complications is low but you are smart to ask this important question.

I hope this helps.

Michael C. Edwards, MD


Yes it is possible to have breast augmentation with Factor 5 Leiden syndrome. However it is essential that you be cleared by your Hematologist and that the doctor communicate with your plastic surgeon about peri operative management. Expect to be treated with Lovenox which may increase chances for peri operative bleeding slightly.

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