Glossary of terms: Injectables and Dermal Fillers

Acquamid

Injectable hydrogel composed of 97.5% apyrogenic water bound to 2.5% cross-linked polyacrylamide used as a dermal filler. Not U.S. FDA approved.

Amphadase

A cow derived (bovine) form of injectable hyaluronidase. U.S. FDA approved.

Anesthesia

A medical treatment to have pain or other discomfort blocked, or an area of the body numbed. Aesthesia comes in many forms including topical, local, oral, regional and general.

Anika CTA

See Elevess.

Anti-viral

A medication that can be given prior to dermal filler injections to decrease the risk of developing viral sores in those prone to outbreaks.

Artecoll

Also known as ArteSense. A collagen-based dermal filler with suspended polymethly methacrylate microspheres available outside the U.S. Not U.S. FDA approved.

ArteFill

A dual-acting injectable dermal filler containing 20% polymethyl methacrylate microspheres and 80% purified bovine collagen gel with lidocaine, an anesthetic. U.S. FDA approved.

ArteSense

See Artecoll.

Axillary

Referring to the underarm region.

Belotero

A hyaluronic acid dermal filler. Also known as Belotero Basic and Belotero Soft. Not U.S. FDA approved.

Betacaine

The brand name of a topically applied 5% lidocaine anesthetic cream. U.S. FDA approved.

Bio-alchamid

An injectable comprised of 96% water and 4% synthetic reticulate polymer (poly-Alkyl-Imide). Not U.S. FDA approved.  

Bioplastique

Injectable comprised of solid silicone microspheres suspended in a hydro-gel solution. Not U.S. FDA approved.

Botox

Brand name of Botulinum Toxin Type A FDA approved for use of select neurological conditions and severe underarm sweating. Botox Cosmetic is the brand name for cosmetic indications. U.S. FDA approved.

Botox Cosmetic

Brand name of Botulinum Toxin Type A used for cosmetic injectable treatments. U.S. FDA approved.

Botulinum Toxin

A neurotoxin protein produced by the bacterium clostridium botulinum. In two specific strains, type A and type B, it is used in minute doses both to treat painful muscle spasms, and as a cosmetic treatment.

Botulinum Toxin Type A

The form of botulinum toxin in Botox and Botox Cosmetic (U.S. FDA approved), Reloxin and PureTox (Not U.S. FDA approved), used cosmetically to prevent frown lines and facial creases.

Botulinum Toxin Type B

The form of botulinum toxin in Myobloc. Not U.S. FDA approved for cosmetic injections.

Bovine Collagen

Derived from bovine (cows), a highly purified collagen used in the manufacture of Zyderm and Zyplast.  

Calcium hydroxylapitite

A microcrystalline form of calcium and phosphorus, similar to naturally occurring components of bone and other tissue. Comprises Radiesse. dermal filler.

Captique

Injectable hyaluronic acid based dermal filler. U.S. FDA approved.

Carboxytherapy

Injection of carbon dioxide for cosmetic purposes, namely to treat cellulite. Not U.S. FDA approved.

Cellulite

A skin condition that results in a dimpling or rippling of the skin, commonly on the buttocks, thighs and hips, sometimes on the abdomen or upper arm.

Collagen

Connective tissue component of skin. U.S. FDA approved collagen dermal fillers include Cosmoderm and Cosmoplast (synthetically derived), Zyderm and Zyplast (bovine collagen). Evolence (porcine collagen) is not U. S. FDA approved.

Compounding

Combining one or more medication with other medications or inert ingredients to provide treatment. Compounded pharmaceuticals are not U.S. FDA approved.

Cosmetic Medicine

A term used to describe medically-based treatments that enhance or improve appearance.

Cosmoderm

The brand name for an injectable collagen - based dermal filler. U.S. FDA approved.

Cosmoplast

The brand name for an injectable collagen - based dermal filler. U.S. FDA approved.

Dental block

A local injection anesthetic method that numbs the mouth and peri-oral area.

Dermadeep

Hyaluronic acid - based dermal filler with added acrylic hydrogel (a non-resorbable component). Not U.S. FDA approved.

Dermagen

A mineral-based dermal filler comprised of silica and oxygen. Not U.S. FDA approved.

Dermal filler

An injected or implanted medical device that plumps or shapes the skin.

Dermalive

Hyaluronic acid - based dermal filler with added acrylic hydrogel (a non-resorbable component). Not U.S. FDA approved.

Dysport

see Reloxin.

Elevess

A hyaluronic acid - based dermal filler. U.S. FDA approved.

Emla

A topical anesthetic cream with 2.5% concentrations of each lidocaine and prilocaine. U.S. FDA approved.

Evolence

A porcine (pig) based collagen dermal filler. Not U.S. FDA approved.

Fat

The common term for adipose, or human fatty tissue.

Fat Injection

Injecting a human’s own fat, which has been removed and processed, to enhance or reshape soft tissue.

FDA

The U.S. Food and Drug Administration, a division of the U.S. Department of Health and Human Services. All medical devices and pharmacological agents (medications) must obtain U.S. FDA approval to be legally administered in the U.S.

Fine Lines

see Restylane Touch.

General Anesthesia

A sensation of total unconsciousness, so that no pain or discomfort is felt while under the influence of general anesthesia. Generally administered via inhalation, although is some cases can be achieved intravenously.

Glabella

The space between the eyebrows and above the nose, where muscle movement commonly results in vertical frown lines.

Granuloma

A small bump that can be seen or felt beneath the skin that can result from particle-based dermal fillers.

Hyaluronic acid

Also called Hyaluronan or Hyalronate, a chief component of cellular matter, particularly connective tissue in the human body. Synthetic hyaluronic acid is the chief component of the U.S. FDA approved dermal fillers Restylane, Hylaform, Juvederm Ultra and Juvederm Ultra Plus, Elevess and Perlane, and of Restylane Touch and Restylane SubQ (not U.S. FDA approved).

Hyaluronidase

A family of enzymes that degrades hyaluronic acid. Used to diminish the results of hyaluronic acid injections in a shorter period of time than the natural absorption process of hyaluronic acid dermal fillers. FDA approved injectable hyaluronidase includes the brand names Vitrase, Amphadase and Hylenex.

Hylaform

The brand name for an injectable hyaluronic acid - based dermal filler. U.S. FDA approved.

Hylaform Plus

See Hylaform.

Hylan

Known as Rofilan, a dermal filler comprised of non-animal stabilized hyaluronic acid. Not U.S. FDA approved.

Hylenex

An engineer form of human compatible injectable hyaluronidase. U.S. FDA approved.

Hyperhidrosis

A medical condition of excessive perspiration.

Injection Lipolysis

See mesotherapy.

Intravenous

The delivery of a liquid medication or other medical substance directly into a vein.

Juvederm

The brand name for an injectable hyaluronic acid - based dermal filler. U.S. FDA approved.

Juvederm Ultra

The brand name for an injectable hyaluronic acid - based dermal filler used for fine to medium depth wrinkle correction. U.S. FDA approved.

Juvederm Ultra Plus

The brand name for a more robust cross-linked formulation of an injectable hyaluronic acid - based dermal filler used for volumizing and correcting deeper folds and wrinkles. U.S. FDA approved.

Lecithin

Lecithin is a fatlike substance called a phospholipids commonly used in mesotherapy. It is produced by the liver and protects cells from oxidation and largely comprises the protective sheaths surrounding the brain. It is U.S. FDA approved for human consumption, but it is not U.S. FDA approved for injection.

Lidocaine

A common anesthetic agent. Exposure to excessive quantities can result in neurological events such as dizziness, tremor or seizure, or cardiac events such as hypotension (drop in blood pressure), arrhythmia or cardiac arrest.

Lipoatrophy

The medical term for fat loss. Facial lipoatrophy can be one of the complications of HIV.

Lipodissolve

The brand name for a cosmetic procedure (injection lipolysis) in which various non-FDA approved drug mixtures, often including phosphatidylcholine or phosphatidylcholine sodium deoxycholate are injected through a series of treatments to purportedly reduce fat. Not U.S. FDA approved.

Lipolysis

The breakdown of fat stored in the fat cells.

Lipostabil

The brand name for a cosmetic procedure (injection lipolysis) in which various non-FDA approved drug mixtures, often including phosphatidylcholine or phosphatidylcholine sodium deoxycholate are injected through a series of treatments to purportedly reduce fat. Not U.S. FDA approved.

Local anesthesia

Blocks the sensation of pain or discomfort in a specific local area.

L.M.X.

An over the counter, topical anesthetic cream containing 4% lidocaine. U.S. FDA approved.

Mesoderm

Commonly reference to the middle layer of cells, or skin. The area primarily injected in mesotherapy treatment.

Mesotherapy

A procedure in which various non-FDA approved drug mixtures, often called PCDC including phosphatidylcholine or phosphatidylcholine sodium deoxycholate are injected into patients to remove fat. Also called injection lipolysis. Commonly puroported as an anti-aging treatment. Not U.S. FDA approved.

Microspheres

Spherical particles composed of various natural and synthetic materials with diameters in the micrometer range.

Myobloc

The brand name for a Botulinum Toxin Type B injection. Not U.S. FDA approved for cosmetic purposes.

NASHA

The acronym for Non-Animal, Stabilized Hyaluronic Acid.

Necrosis

The accidental death of cells and living tissue. There are many causes of necrosis including prolonged injury, infection or inflammation.

Nerve block

A form of anesthesia that involves the injection of a local anesthetic or a neurolytic agent into or near a peripheral nerve, a sympathetic nerve plexus, or a local pain-sensitive trigger point to numb a region.

Numbing cream  

 

A form of anesthetic by topical cream to numb tissue prior to injections or laser procedures.

Off-label

The practice of prescribing drugs or medical treatment for a purpose similar too, but specifically not defined by a drug's U.S. FDA approved label.

Oral block

A form of anesthesia by local anesthetic used to numb a region to be treated

Palmar

Concerning the region of the palms of the hands

Particle-based

Containing microscopic particles or spheres

Perlane

The brand name for an injectable hyaluronic acid - based dermal filler. U.S. FDA approved.

Phosphatidylcholine

A major component of lecithin, used in mesotherapy treatment

Phosphatidylcholine Sodium Deoxycholate

A major component used in mesotherapy t reatment

Polyacrylamide

Highly water absorbent, soft formed gel that is used in making contact lenses, as a thickener or suspending agent. Not U.S. FDA approved as a dermal filler.

Poly-L-lactic acid

A biodegradable, biocompatible synthetic polymer from the alpha hydroxy acid (AHA) family that has been widely used for many years in dissolvable stitches, bone screws, and facial implants and is the primary component of Sculptra.

Polymethyl methacrylate (PMMA)

Nonbiodegradable, chemically inert component of dermal filler used under the brand of ArteFill. The results of PMMA injections are permanent.

Porcine Collagen

Derived from porcine (pig) tendons, a highly purified collagen used in the manufacture of Evolence.

Prevelle

A hyaluronic acid dermal filler. Not U.S. FDA approved.

Prevelle Plus

A hyaluronic acid dermal filler with added lidocaine for pain management. Not U.S. FDA approved.

Prilocaine

A local anesthetic agent often used in dentistry, intravenous regional anesthetic and as a component of topical anesthetic cream.

Ptosis

The medical term for drooping eyelids.

Puragen

The brand name for an injectable non-animal, hyaluronic acid, - based dermal filler derived from bacterial fermentation used for wrinkle correction. Not U.S. FDA approved.

Puragen Plus

Puragen dermal filler with added lidocaine for pain management. Not U.S. FDA approved.

PureTox

The brand name for an injectable botulinum toxin type A, used for wrinkle correction. Not U.S. FDA approved.

Radiance

Known as Radiesse

Radiesse

The brand name for an injectable calcium hydroxylapatite, - based dermal filler. U.S. FDA approved.  

Regional Anesthesia

Blocking pain or other discomfort to a specific region of the body, such as a limb.

Reloxin

The brand name for an injectable botulinum toxin Type A, used for wrinkle correction. Approved in Europe under the brand name Dysport. Not U.S. FDA approved.

Restylane

The brand name for an injectable hyaluronic acid - based dermal filler. U.S. FDA approved.

Restylane SubQ

The brand name for an injectable hyaluronic acid - based dermal filler used for the correction of deep facial folds and treatment of lipoatrophy. Not U.S. FDA approved.

Restylane Touch

The brand name for an injectable hyaluronic acid - based dermal filler used for the correction of very lines and wrinkles. Not U.S. FDA approved.

Reviderm Intra

A dermal filler comprised of non-animal stabilized hyaluronic acid with suspended carbohydrate complex microspheres. A semi-permanent filler, the microspheres fully resorb in months. Not U.S. FDA approved.

Rofilan

A dermal filler comprised of non-animal stabilized hyaluronic acid. Also known as Hylan. Not U.S. FDA approved.

Sculptra

The brand name for an injectable poly-L-lactic acid - based dermal filler, used for a condition known as lipoatrophy, or facial wasting. U.S. FDA approved for treatment of lipoatrophy.

Silicone

Inorganic and organic polymers combined for a myriad of moisture resistant uses including cosmetics and breast implants. When injected, silicone is permanent. Not U.S. FDA approved for cosmetic injection.

ilikon 1000

The brand name for sterile, non-pyrogenic, clear, colorless silicone oil FDA approved only for use during vitreoretinal surgery. Use as a permanent silicone dermal filler is not U.S. FDA approved.

SilSkin

The brand name for a permanent silicone - based dermal filler. Not U.S. FDA approved.

SubQ

Abbreviation for subcutaneous, meaning beneath the skin. Also see Restylane SubQ.

Topical anesthetic

A local anesthetic agent applied to numb the surface of an tissue, such as skin or gums.

Tetracaine

A potent local anesthetic often used topically.

Valtrex

The brand name for an antiviral drug commonly used to slow the spread of herpes. U.S. FDA approved.

Vitrase

A sheep derived (ovine) form of injectable hyaluronidase. U.S. FDA approved.

Zyderm

The brand name for an injectable bovine collagen-based dermal filler. U.S. FDA approved.

Zyplast

The brand name for an injectable bovine collagen-based dermal filler. U.S. FDA approved.


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