Study compares injectables aimed at reducing wrinkles

August 7, 2011

Study compares injectables aimed at reducing wrinkles
Study compares injectables aimed at reducing wrinkles

According to the American Society for Aesthetic Plastic Surgery, more than 2.4 million people got injectables of Botox or Dysport last year to reduce fine lines on the face.

For the past decade, Botox, which is a version of botulinum toxin type A that temporarily weakens or paralyzes muscles that cause wrinkles, has been the most popular cosmetic nonsurgical procedure.

However, a new version of the drug, called Dysport, was recently found to deliver better results in some cases.

A study conducted by scientists at the University of California San Francisco and published in the Archives of Facial Plastic Surgery compared the effectiveness of the two injectables in reducing the appearance of crow's feet, or the small wrinkles that are common around the eye area.

For the so-called "split face" study, 90 volunteers had Botox injections on one side of their face and Dysport injections on the other. After one month, 67 percent of those who received the injections said that the Dysport side of their face looked better.

"From our findings, it's clear that there's a better smoothing effect and clearing of lines around the eyes with Dysport," the study's co-author told HealthDay. "But does that also mean that Dysport is better at achieving the same thing around the mouth or forehead or neck? We really can't make that conclusion."

Botox and Dysport are both approved by the U.S. Food and Drug Administration and are not associated with any severe safety risks.

"The most important aspect of using these different botulinum toxins is not which one you get, but making sure that you are being injected by a reputable and respected physician who does a lot of these injections," A professor of facial plastic surgery at Washington University in Saint Louis, told ABC News.

Experts say that the first step to ensuring positive results from cosmetic procedures such as injections of Botox or Dysport is to choose a trained, board certified plastic surgeon or dermatologist.

Those looking to research the benefits of using a particular injectable cosmetic treatment may also visit InjectableSafety.org for unbiased information.


The mission of the American Society for Aesthetic Plastic Surgery (ASAPS) includes medical education, public education and patient advocacy. Plastic Surgery News Briefs are summaries of current stories found through various news and magazine outlets that relate to or mention plastic surgery and cosmetic procedures. The views expressed in these news articles do not necessarily reflect the opinions of ASAPS, but are merely published as an educational service to our members and the general public. For additional information on these subjects and other plastic surgery related topics, please go to www.surgery.org

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About ASAPS
The American Society for Aesthetic Plastic Surgery (ASAPS), is recognized as the world’s leading organization devoted entirely to aesthetic plastic surgery and cosmetic medicine of the face and body.  ASAPS is comprised of over 2,600 Plastic Surgeons; active members are certified by the American Board of Plastic Surgery (USA) or by the Royal College of Physicians and Surgeons of Canada and have extensive training in the complete spectrum of surgical and non-surgical aesthetic procedures. International active members are certified by equivalent boards of their respective countries. All members worldwide adhere to a strict Code of Ethics and must meet stringent membership requirements.

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